Drug Standards
Selleck Chemical LLC Lenalidomide S1029-1g
Lenalidomide is a TNF- secretion inhibitor with IC50 of 13 nM in PBMCs Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) and it causes selective ubiquitination and degradation of two lymphoid transcription factors IKZF1 and IKZF3 by the CRBN-CRL4 ubiquitin ligase Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis
![eMolecules Efavirenz | Combi-Blocks | 154598-52-4 | MFCD05662344 | 315.680 | C14H9ClF3NO2 | 97.000 | FC(F)(F)[C@]1(OC(=O)Nc2ccc(Cl)cc12)C#CC1CC1 | 25g | 342875826](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00128114-342875826.PNG-250.jpg)
eMolecules Efavirenz | Combi-Blocks | 154598-52-4 | MFCD05662344 | 315.680 | C14H9ClF3NO2 | 97.000 | FC(F)(F)[C@]1(OC(=O)Nc2ccc(Cl)cc12)C#CC1CC1 | 25g | 342875826
Efavirenz | Combi-Blocks | 154598-52-4 | MFCD05662344 | 315.680 | C14H9ClF3NO2 | 97.000 | FC(F)(F)[C@]1(OC(=O)Nc2ccc(Cl)cc12)C#CC1CC1 | 25g | 342875826
Med Vet International Diclofenac Sodium, .1% Ophth Solution, 5mL
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
RX diclofenac sodium, .1% ophth solution, 5ml
eMolecules 1189986-72-8 | Medchem Express | Diphenhydramine-d6 (hydrochloride) | 1mg | 791206479 | HY-B0303AS | 297.86 | C17H22ClNO
Medchem Express | c-Fms-IN-8 | 5mg | 773121845 | HY-119942 | 1255303-58-2 | 462.546 | C27H30N2O5
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eMolecules Building Block Tool
Cayman Chemical De-Boc-CabazItaxel 1mg
A potential impurity in commercial preparations of cabazitaxel; has been used in the synthesis of tubulin-targeting fluorescent dyes
![Medchemexpress LLC 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quin azolinyl], | 2223677-64-1 | 50mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quin azolinyl], | 2223677-64-1 | 50mg
Afatinib impurity 34 is an impurity of Afatinib (HY-10261)
Medchemexpress LLC Itacitinib | 1334298-90-6 | 100.0% | 553.51 | 5 MG
Itacitinib (INCB039110) is an orally active and selective inhibitor of JAK1, exhibiting significant selectivity over JAK2, JAK3, and TYK2. It is primarily used in the research of myelofibrosis. This product is for research purposes only and has not been fully validated for medical applications.
- Orally active and selective JAK1 inhibitor
- IC50 of 2 nM for human JAK1
- Over 20-fold selectivity for JAK1 over JAK2
- Over 100-fold selectivity over JAK3 and TYK2
- Used in myelofibrosis research
- For research purposes only
Medchemexpress LLC Keto-itraconazole | 112560-33-5 | MFCD08063772 | 98.4% | 719.62 g·mol^-1 | C35H36Cl2N8O5 | 5 MG
Keto-itraconazole is the primary human metabolite of itraconazole used in research as a potent cytochrome P450 3A (CYP3A) inhibitor. It is supplied as a high-purity solid for in vitro pharmacology, metabolism, and drug-drug interaction studies. Typical small pack sizes are provided for lab-scale experiments.
- Potent CYP3A inhibitor (unbound IC50 ≈ 4.6 nM in human liver microsomes with midazolam).
- High purity solid suitable for in vitro assays (reported purity 98.4%).
- Molecular formula C35H36Cl2N8O5 and molecular weight 719.62 g·mol^-1.
- Suitable for liver microsome incubations and drug-drug interaction studies.
- Available in small quantities for research use.
Cambridge Isotope Laboratories gamma-HCH (gamma-BHC) (lindane) (13C6 99%) 100 ug/mL in nonane 1 2 mL
gamma-HCH (gamma-BHC) (lindane) (13C6 99%) 100 ug/mL in nonane 1 2 mL
![eMolecules 1184-88-9 | Sodium pivalate | Oakwood Chemical | MFCD00064202 | 124.115 | C5H9NaO2 | 95.000 | [Na+].CC(C)(C)C([O-])=O | 250mg | 853685506](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000126929.jpg-250.jpg)
eMolecules 1184-88-9 | Sodium pivalate | Oakwood Chemical | MFCD00064202 | 124.115 | C5H9NaO2 | 95.000 | [Na+].CC(C)(C)C([O-])=O | 250mg | 853685506
Sodium pivalate | Oakwood Chemical | 1184-88-9 | MFCD00064202 | 124.115 | C5H9NaO2 | 95.000 | [Na+].CC(C)(C)C([O-])=O | 250mg | 853685506
Medchemexpress LLC N-(3-Acetyl-4-(2-hydroxy-3-(isopropylamino)propoxy-1,1,2,3,3-d5)phenyl)butyramide | 1189500-68-2 | 897231 | 99.7% | 341.46 | 1 MG
Acebutolol-d5 is the deuterium labeled Acebutolol. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Glycopyrrolate | 596-51-0 | 398.33 | 10 MM 1 ML
Glycopyrrolate (Glycopyrronium bromide), a quaternary ammonium derivative, is a muscarinic receptor antagonist. It has a bronchoprotective effect and produces a beneficial effect on blood pressure. Glycopyrrolate can be used for the research of bronchial diseases.
- Muscarinic receptor antagonist
- Bronchoprotective effect
- Beneficial effect on blood pressure
- Can be used for the research of bronchial diseases
Medchemexpress LLC Avotaciclib trihydrochloride | 1983984-01-5 | 99.6% | 390.66 g/mol | C13H14Cl3N7O | 5 MG
Avotaciclib trihydrochloride is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor provided as a research reagent for preclinical cancer studies. It inhibits tumor cell proliferation and induces apoptosis in multiple tumor cell lines and is supplied as the trihydrochloride salt.
- Orally active CDK1 inhibitor for preclinical research.
- Useful in studies of lung and pancreatic cancer cell lines.
- Trihydrochloride salt form for enhanced solubility.
- High purity (99.6% by HPLC).
- Molecular weight 390.66 g/mol; formula C13H14Cl3N7O.
- Supplied as a 5 mg research-grade sample.
- For research use only; not for human consumption.
Cayman Chemical Montelukast 100mg
A CysLT1 receptor antagonist (IC50 = 4.9 nM in HEK293 cell membranes expressing the human receptor); selective for CysLT1 over CysLT2 receptors (IC50 = >10,000 nM in COS-7 cell membranes expressing the human receptor); inhibits LTD4-induced bronchoconstriction in anesthetized guinea pigs (ED50 = 69 nmol/kg, p.o.); inhibits ovalbumin-induced airway hyperresponsiveness and increases in the number of total cells and eosinophils in BALF in a mouse model of allergic asthma at 3 and 10 mg/kg
Selleck Chemical LLC Quetiapine Fumarate 100mg 111974-72-2 ICI-204636
Quetiapine Fumarate (ICI-204636) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression and shows affinity for various neurotransmitter receptors including serotonin, dopamine, histamine, and adrenergic receptors. *For Research & Development use only. Product is not intended for drug, household, or human consumption.